• Image of melanoma tumor
      Confocal microscope image of a melanoma tumor. Nuclei are blue, tumor associated macrophages are green and vasculature is red. (Bosenberg and O'Hern labs)
    • Image of students working in groups
      Hands-on workshop run by visiting faculty speakers Profs. David and Jane Richardson, on the capabilities and uses of various software suites.
    • Image of microfluidics setup
      A microfluidics setup, which comprised part of a demonstration during the 2012 annual meeting of the NSF Physics of Living Systems Student Research Network, hosted at Yale.
    • Image of optics
      Part of a setup to conduct single molecule fluorescence measurements.
    • Image of force versus extension measurements
      Force versus extension measurements of nucleosomes using a single molecule spectroscopy setup (Mochrie lab).



The Program in Physics, Engineering, and Biology (PEB) enables transformative research and teaching initiatives.

Faculty, students, and postdocs in PEB are committed to a new paradigm that transcends traditional boundaries both between disciplines and between research, teaching, and learning. We have a variety of activities set in place that showcase the innovative ways in which we achieve this.

PEB works closely with Yale’s new Quantitative Biology Institute.


Our current faculty members come from more than 20 departments in the Faculty of Arts and Sciences, The School of Medicine, and The School of Engineering and Applied Science. Many of the faculty have ongoing research collaborations, which focus on exploring  exciting problems in biology using quantitative, physical approaches.


The research encompasses a broad range of time and length scales and frequently bring together wet lab work with theory, computation, and modeling.  Our research groups explore one or more of the following research thrusts:

  • imaging, image analysis and optics
  • biological sensing and computing
  • mechanobiology and force generation
  • omics, data mining, and multi-dimensional analysis
  • dynamical systems and processes
  • simulations and modeling of biological processes
  • biomaterials and bioengineering

Anyone whose research or teaching interests mesh with our program’s is welcome to participate.