What can we learn from imaging cells, tissues, and organisms? Labs working in imaging and optics are pushing the limits of light, fluorescence, and electron microscopy approaches to create images and movies that with higher spatial and temporal resolution. Once the images are acquired, researchers working in the area of image analysis are discovering new ways to analyze and quantify these images.
Imaging Biological Systems
Featured Research
Dynamic speckle illumination microscopy with tailored speckle statistics
SeungYun Han ‘26
he/him
Applied Physics (Cao Lab)
Wavefront Shaping of Light in Scattering Media
Rohin McIntosh ‘27
he/him
Physics (Cao Lab)
Understanding ultrafast peptide dynamics in cells using Fast Relaxation Imaging
Raibat Sarker ‘28
he/him
Chemistry (Davis Lab)
Faculty
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Sean Barrett
Professor; Physics and Applied PhysicsResearch Interests: Experimental condensed matter physics; NMR method development -
Julien Berro
Associate Professor: Molecular Biophysics & Biochemistry and Cell BiologyResearch Interests: Actin and cytoskeleton; clatherin mediated endocytosis; mathematical modeling combined with experiment; imaging -
Joerg Bewersdorf
Professor: Cell Biology, Biomedical Engineering, and PhysicsResearch Interests: Super resolution imaging; nanoscopy -
Hui Cao
Professor; Applied Physics, Physics, and Electrical EngineeringResearch Interests: Biophotonics; Nanophotonics; Complex optical materials and phenomena -
Alicia Che
Assistant Professor; PsychiatryResearch Interests: Structure and function of cortical networks: neuronal circuits; optical imaging -
Caitlin Davis
Assistant Professor; ChemistryResearch Interests: Using time-resolved spectral imaging at multiple scales, from in vitro to single cell to whole organism, to make connections between molecular mechanisms and cellular function -
Paul Forscher
Professor; Molecular, Cellular & Developmental BiologyResearch Interests: Actin assembly; cytoskeletal protein dynamics; cellular motion; microscopy -
Scott Holley
Professor; Molecular, Cellular & Developmental BiologyResearch Interests: The systems biology, biomechanics and molecular biophysics of early spinal column development -
Joe Howard
Professor; Molecular Biophysics & Biochemistry and PhysicsResearch Interests: Microtubules and molecular motors. Branching morphogenesis of neurons. Motility of cilia and flagella. Nerve nets. -
Aaron Kuan
Assistant Professor; Neuroscience and Biomedical EngineeringResearch Interests: Electron microscopy and X-ray imaging techniques to enable 3D imaging of neuronal circuits combined with behavior and functional imaging to reveal how circuit connectivity underlies brain activity and cognition. -
Roy Lederman
Assistant Professor; Statistics and Data ScienceResearch Interests: Cryo-EM; numerical analysis and signal processing; geometry of data; computational biology algorithms; mathematics of data science -
Liang Liang
Assistant Professor; NeuroscienceResearch Interests: Synaptic and neural circuit mechanisms underlying visual information processing; combining recording of neural activity in awake behaving animals, image processing, and computational modeling -
Yimin Luo
Assistant Professor; Mechanical Engineering & Materials ScienceResearch Interests: Regulated cell alignment and tissue organization are vital in health and disease. To systematically investigate how cells respond to patterns, we achieve precise control over their arrangement through molecularly defined scaffolds. We innovate a continuous imaging platform tracking thousands of cells over days. Leveraging reams of data, we develop a hybrid procedure that utilizes statistical learning approaches to extend the state-of-the-art physics models. -
Zongming Ma
Professor; Statistics and Data ScienceResearch Interests: Developing machine learning and statistical tools to gain biological insights from spatial and single-cell data -
Nikhil Malvankar
Associate Professor; Molecular Biophysics & BiochemistryResearch Interests: We are developing electronic Imaging & Control of Microbial Functions, by studying how environmentally and clinically important microbes build & use hair-like “nanowires” to export electrons outside their cell body, during respiration, communication, and pathogenesis and by tuning nanowire conductivity using light, pressure, temperature, electromagnetic fields, and non-natural ‘click’ chemistry. -
Kirstin Meyer
Assistant Professor; Molecular, Cellular, and Developmental BiologyResearch Interests: We seek to understand molecular mechanisms of emergent gene regulatory behavior, with a focus on temporal information transmission, mechanosensing, and chromatin biophysics. -
Simon Mochrie
Professor; Physics and Applied PhysicsResearch Interests: Quantitative microscopy and image analysis. Chromatin organization and dynamics. Nuclear envelope physics. Phase transitions of soft matter -
Binyam Mogessie
Assistant Professor; Molecular, Cellular & Developmental Biology and Obstetrics, Gynecology & Reproductive SciencesResearch Interests: The Mogessie lab studies cytoskeletal organization and function with a special focus on chromosome segregation in mammalian eggs and the molecular origins of female reproductive aging and infertility. -
Michael Murrell
Associate Professor; Biomedical Engineering and PhysicsResearch Interests: Non-equilibrium thermodynamics, active matter, biophysics, synthetic biology, cytoskeletal mechanics. -
Hesper Rego
Associate Professor; Microbial PathogenesisResearch Interests: Imaging (including building microscopes), single-cell level experiments, mycobacterial infections, drivers of heterogeneity -
Xiaolei Su
Assistant Professor; Cell BiologyResearch Interests: Membranes, phase separation, and regulation of immune signaling; single molecule imaging and cell engineering -
Jing Yan
Assistant Professor, Molecular, Cellular & Developmental BiologyResearch Interests: Imaging and modeling the developmental process of bacterial communities, characterizing and understanding the soft matter properties of bacterial biofilms, designing new bioinspired materials and surfaces